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Posts Tagged ‘Northeastern University’

Photo: David L Ryan/ Boston Globe Staff.
A view of a Forbes sea star at Northeastern University’s Ocean Genome Legacy Center.

As I was reading today’s story, an image kept coming to mind: an image of someone in a burning house running out with a few precious items.

You’ll see why when you read Kate Selig’s article at the Boston Globe on a genome bank.

“On a rocky outcropping a few miles northeast of Boston Harbor,” she writes, “scientists are racing to build a library of tissue and DNA from ocean creatures — before it is too late. It’s a last-ditch effort. As global warming drives ocean temperatures ever higher, some species have vanished and the populations of others have plummeted. If climate change continues unchecked, many marine species could face a mass extinction, rivaling the worst in earth’s history.

“To preserve the oceans’ historical record, researchers in Nahant, a peninsular town jutting into the Atlantic, are collecting samples from marine organisms around the world and distributing them to scientists.

“ It’s not difficult to do,’ said Dan Distel, a marine biologist who serves as the director of Northeastern University’s Ocean Genome Legacy Center. ‘It’s not expensive to do. And of course, if we miss the opportunity, it’s too late.’ …

“The Nahant collection has informed hundreds of studies, providing a baseline understanding of how species are doing while also tracking global trends. The repository houses common local species, such as spiky sea urchins and flatfish with their eyes trained skyward. But there are also some ‘real weirdos,’ as Distel described them. A prized specimen from the Philippines is a preserved giant shipworm, a glistening, tubular creature that lives in a tusk-like shell. A petite marine mussel the size and shape of a plump grain of rice rests in a small jar.

“A whiteboard at its entrance decorated with drawings of fish, sea stars, and a crab displays the current count: over 31,000 DNA samples and 28,000 tissue samples.

“Distel is the ringmaster behind the menagerie. … In addition to his work at the center, he has dedicated much of his career to studying shipworms, a type of worm-like clam notorious for gnawing through submerged wood. Distel was part of an international team that discovered a live specimen of the giant shipworm, a find that drew international attention. …

“ ‘These guys are a great example of a nearly extinct species,’ he said, with a touch of reverence. ‘There’s only one place in the world where we know they can still be found.’

“As humanity continues to burn fossil fuels, the world’s oceans have stood as a bulwark to the most extreme impacts of climate change by swallowing much of the excess heat trapped by greenhouses gases. But that has come at a staggering cost.

“The surface layer of the ocean has warmed by about 1.5 degrees Fahrenheit over the past century. In the Gulf of Maine, which is warming much faster than most ocean surfaces on the planet, the higher temperatures are forcing out lobsters, altering the migration patterns of whales, and fueling a population boom of invasive green crabs.

“The center was founded in 2004 by Donald Comb, a Massachusetts biotechnology pioneer. … Comb, who loved the oceans, decided to put up the funds to build a biorepository focused on marine species. The center became the first ocean-focused public DNA bank in the United States. …

“Large samples preserved in jars are stored in shelving units and a repurposed tool chest. They infuse the center with what students call ‘the low tide smell.’

“The real action takes place in the freezer room. Four mechanical freezers, rigged with alarms and known as ‘minus 80s’ for their low temperatures, store small tubes that contain the complete genome of an organism. A single freezer can fit thousands of samples. The center also has a liquid nitrogen freezer that chills samples so quickly that living bacteria can be revived. …

“Angela Jones, a Northeastern PhD candidate in marine and environmental sciences, has supplied the center with samples from her doctoral research on sea stars, studying two species in New England that have undergone steep population declines. …

” ‘It’s important to understand what the species are like now so that we can understand how they change under worsening conditions,’ she said.”

More at the Globe, here.

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I liked a recent story by Steve Annear at the Boston Globe. It was about a student who was planning to run the New York Marathon — while knitting — to raise money for medical research.

“At first,” writes Annear, “the idea of knitting a scarf while running the length of the New York City Marathon was merely a joke shared between Meredith Parmalee and her former employer, We Are Knitters.

“But as the Northeastern University senior continued to ponder the concept, she realized she could use the attention-grabbing feat to bring awareness to, and raise funds for, the Leukemia and Lymphoma Society. …

“ ‘It helps distract me from thinking about running . . . and my legs hurting and my arms hurting. It helps me keep my mind off of it.’

“Parmalee, 22, is being sponsored by We Are Knitters, where she did a co-op job for school, to run with the charity group Team in Training. … As she jaunts through New York Sunday, Parmalee will use a technique called ‘finger knitting,’ rather than two long needles, to weave a long scarf.

“To finger knit, Parmalee starts by making a slipknot around her index finger, and then loops the yarn around each of her three other fingers, skipping the thumb. She then brings the ‘yarn tail’ back around each finger, so there are two loops on each, and slips the second loop off each finger, starting with the index finger.

“She repeats the process, slowly binding the yarn together in tight knots. Making sure she threads the yarn correctly between each appendage requires a certain level of hand-eye coordination, but it also helps Parmalee keep a steady rhythm while she runs. …

“Parmalee said the plan is to have supporters at designated mile markers along the race route so that she can replenish her yarn supply.”

More about Parmalee at the Boston Globe, here. More about about We Are Knitters, here.

Photo: We Are Knitters
Meredith Parmalee plans to use a finger-knitting technique while making a scarf during the New York City Marathon.

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National Public Radio recently featured a researcher who has figured out a way to help people who can’t talk by matching the sounds they are able to make to someone else’s voice and creating a synthetic voice.

“Speech scientist Rupal Patel creates customized synthetic voices that enable people who can’t speak to communicate in a unique voice that embodies their personality.

“Rupal Patel directs the Communication Analysis and Design Laboratory at Northeastern University. She helped found VocaliD, an organization working to help the millions of people who use computerized devices to communicate in unique voices.

“Patel’s technique to move beyond the usual generic male voice. She samples the tones of those with severe speech disorders and matches them with a surrogate talker. By blending the two, the team can create a synthetic voice to match the person using it.”

Check out the NPR story here.

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