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Posts Tagged ‘sense of smell’

Photo: Antony Holvoet/Apopo.
The statue of Magawa, the land-mine-sniffing rat, was unveiled on the eve of International Day for Mine Awareness. Land mines are illegal under international law because they kill so many innocents, but countries still use them. Talented rats will continue to be needed.

Probably most of you have a reason to hate rats, but it’s important to note that rats can not only be useful in science but heroic in helping clear land mines. Today’s article is about a rat that prevented so much death and dismemberment that he’s been honored with his own statue.

Sydney Page writes at the Washington Post, “Although Magawa weighed less than three pounds, his impact was monumental. The African giant pouched rat sniffed out more than 100 land mines during his five-year career, saving countless lives.

“To honor his bravery, a seven-foot statue of Magawa was unveiled [in Cambodia], where he spent his time nose-down on high-stakes missions. Magawa died in 2022, but his legacy lives on.

“ ‘Magawa was one of the best rats we’ve ever had,’ said Michael Raine, a program manager in Cambodia for Apopo — a Belgium-based nonprofit that trains animals to detect land mines. ‘Magawa was calm and focused … he was gentle and friendly with his handlers. He just had the perfect temperament.’

“Born in 2013 at Apopo’s headquarters in Tanzania, Magawa was trained as a ‘HeroRAT,’ learning to harness his strong sense of smell to detect explosives. In 2016, he was relocated to Siem Reap, Cambodia, to begin his career, quickly rising to the top among Apopo’s rats. He even has his own Wikipedia page.

“Raine said Magawa could search a field the size of a tennis court within about 20 minutes — a task that would take a human several days. …

“Apopo trains rats using positive reinforcement, teaching them to identify chemical compounds in explosives, such as trinitrotoluene. When a rat detects a land mine, it scratches the surface, alerting its handler. The rat is then rewarded with a treat, typically a peanut or a slice of banana. …

“ ‘They’re so light they wouldn’t trigger a land mine,’ Raine said. Plus, ‘they have an extremely sensitive sense of smell and they are quite intelligent.’

“Cambodia has one of the world’s highest concentrations of land mines, largely stemming from the Khmer Rouge era in 1979 and the Vietnamese occupation between 1979 and 1989.

“In the past 47 years, land mines in Cambodia have caused about 18,800 deaths and 45,000 injuries. Apopo started training mine-detection rats in 2015, which helped speed up the efforts to locate mines, though an estimated 6 million land mines remain in Cambodia, according to Apopo. … Raine said, ‘Cambodia’s target is to be land mine free by 2030.’

“Magawa’s individual impact is remarkable, Raine said. He cleared more than 1.52 million square feet — roughly 26 football fields — and detected dozens of land mines. In 2020, Magawa became the first rat to receive the PDSA Gold Medal, which rewards animal bravery and devotion to duty. …

“After retiring in 2021, Magawa spent several weeks mentoring younger rats, helping them refine their detection skills by his example. …

“The giant statue of Magawa, hand-carved from stone by local artists, was commissioned by Apopo and unveiled on the eve of International Day for Mine Awareness. In attendance were government officials, including the head of the Cambodian Mine Action and Victim Assistance Authority. Land-mine victims were also present, as well as children from a local school.

“ ‘What Magawa delivered was excellent, and it was a good way to remember him and also remind people in a nice way that there’s still a mine problem here in Cambodia,’ Raine said.”

More at the Post, here.

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From “The Ants Go Marching” song, via Kylie Van Dam.

When I was young, I remember being horrified and fascinated to learn that hospitals sometimes use live maggots in wound care because of their precision.

Maggots clear away gangrene and leave healthy tissue. The UK National Health Service says, “They also help fight infection by releasing substances that kill bacteria and stimulate the healing process.” It’s called biosurgery.

Now researchers are finding that ants also have medical uses. Dino Grandoni has the story at the Washington Post.

“The ant oncologist will see you now.

Ants live in a world of odor. Some species are completely blind. Others rely so heavily on scent that ones that lose track of a pheromone trail march in a circle, until dying of exhaustion.

“Ants have such a refined sense of smell, in fact, that researchers are now training them to detect the scent of human cancer cells.

“A study published []in the journal Proceedings of the Royal Society B: Biological Sciences highlights a keen ant sense and underscores how someday we may use sharp-nosed animals — or, in the case of ants, sharp-antennaed — to detect tumors quickly and cheaply. That’s important because the sooner that cancer is found, the better the chances of recovery.

“ ‘The results are very promising,’ said Baptiste Piqueret, a postdoctoral fellow at the Max Planck Institute for Chemical Ecology in Germany who studies animal behavior and co-wrote the paper. He added, however: ‘It’s important to know that we are far from using them as a daily way to detect cancer.’

“Stretching out their pair of thin sensory appendages atop their heads, the insects detect and deploy chemical cues to do almost everything — find food, swarm prey, spot colony mates, protect young. This chemical communication helps ants construct complex societies of queens and workers that operate so in sync with scent that scientists dub some colonies ‘superorganisms.’

“For his study, Piqueret’s team grafted pieces of a human breast-cancer tumor onto mice and trained 35 ants to associate urine from the tumor-bearing rodents with sugar. Placed in a petri dish, the silky ants (Formica fusca) spent significantly more time near tubes with urine from the ‘sick’ mice compared with urine from healthy ones. …

“The way we diagnose cancer today — by drawing blood, taking biopsies and conducting colonoscopies — is often expensive and invasive. Animal behaviorists are imagining a world in which doctors one day tap species with keen senses to help spot tumors quickly and cheaply.

“Dogs can sniff out the presence of cancer in body odor, past research has shown. Mice can be trained to discriminate between healthy and tumor-bearing compatriots. Nematodes are attracted to certain organic compounds associated with cancer. Even the neurons of fruit flies fire in the presence of certain cancerous cells.

“But ants, Piqueret suggested, may have the edge over dogs and other animals that are time-consuming to train.

“Piqueret conducted the research while studying at the Université Sorbonne Paris Nord in France. During covid lockdowns, he brought silky ants into his apartment outside Paris to continue his experiments. He chose the species because it has a good memory, is easy to train and doesn’t bite (at least not hard). …

“Piqueret’s team plans to test ants’ ability to sniff out the markers of cancer in urine from actual patients. …

“If ants are ever used in cancer screening, Piqueret wants to make one thing clear: No, they will not need to crawl on you.

“ ‘There will be no direct contact between ants and patients,’ he said. ‘So even if people are afraid of insects, it’s fine.’ “

More at the Post, here. Interested in the wonders of ants? Follow this professor: @alexwild.

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